Hofwell Nail Renewal Cream (40% urea)

For the patient's doctor or podiatrist. One page, plain facts. Questions: support@hofwell.com.

What it is

A cosmetic night cream for thick, hard toenails (onychauxis and thickened, dystrophic nails). It softens the built-up nail plate so the patient or a caregiver can trim it with ordinary clippers. It is not a drug and does not treat infection.

Ingredients (1.76 oz / 50 ml jar)

Urea 40%, salicylic acid 0.5%, tea tree oil, vitamin E, shea butter, aloe vera.

How it is used

Application	A small dab on each thickened nail with the supplied spatula, at bedtime. Socks on. Kept on the nail, off the surrounding skin; any excess wiped off.
Frequency	Nightly for about 90 nights to soften; then 2–3 nights a week to keep the nail trimmable.
Trimming	Once the nail cuts without force, usually after 2–4 weeks. No blade is needed before then.
Not for	Broken, ulcerated, red or infected skin. Pause if the skin stings or reddens.

Why it may suit your patient

Urea 40% is an established keratolytic for softening thickened nails (see DermNet NZ, "Medical nail avulsion"; urea ointment in the nonsurgical avulsion of nail dystrophies, PubMed 7379590).
It removes the need to force clippers or tools through a thick nail at home, which is where cuts happen in patients on anticoagulants or with diabetes or neuropathy.
It is intended for between professional visits, not instead of them. Patients with diabetes, PAD or neuropathy should keep their routine foot care.

Evidence on file

Hofwell 30-night photo trial: 913 started, 782 completed, 721 met the verification standard (ages 35–79). Daily standardized photographs, scored blind for thickness, roughness, opacity and discoloration by assessors not employed by Hofwell. 3 in 4 reported trimming with ordinary clippers by week 4. 180 participants continued to week 12.

Hofwell is a cosmetic product. It is not intended to diagnose, treat, cure or prevent any disease. Individual results vary.